COMPREHENSIVE APPLICATION OF GRAPHENE: EMPHASIS ON BIOMEDICAL CONCERNS


Development of the triazole-fused pyrimidine derivatives as highly potent and reversible inhibitors of histone lysine specific demethylase 1 (LSD1/KDM1A)

Histone lysine specific demethylase 1 (LSD1) has been recognized as an important modulator in post-translational process in epigenetics.Dysregulation of LSD1 has been implicated in the development of various cancers.Herein, we report the discovery of the hit compound 8a (IC50 = 3.93 μmol/L) and further medicinal chemistry efforts, leading to the

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PROGRAM PENGEMBANGAN BIMBINGAN KONSELING UNTUK MENINGKATKAN KECAKAPAN PENGARAHAN DIRI (SELF DIRECTION) PADA MAHASISWA UIN RADEN INTAN LAMPUNG

Students currently in a life full of challenges, the growing need to have an identity and maturation of career choices.Therefore they are expected to be continuously on a variety of changes, diversity of choices, competition, and the demands of relentless self-adjustment, both at the campus, local, Stands national, and global levels.Students who do

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Vertical Wind Shear and Ocean Heat Content as Environmental Modulators of Western North Pacific Tropical Cyclone Intensification and Decay

ABSTRACT: A general framework in which Ocean Heat Content (OHC) Fridge Freezer may modulate tropical cyclone intensification and decay in conjunction with Vertical Wind Shear (VWS) as the primary environmental control is formulated in terms of a two-dimensional phase diagram.case studies of the life cycles of three tropical cyclones during the Impa

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Killing malignant melanoma cells with protoporphyrin IX-loaded polymersome-mediated photodynamic therapy and cold atmospheric plasma

Mian Wang,1 Benjamin M Geilich,2 Michael Keidar,3 Thomas J Webster1,4 1Department of Chemical Engineering, 2Department of Bioengineering, Northeastern University, Boston, MA, 3Department of Mechanical and Aerospace Engineering, George Washington University, Washington, DC, USA; 4Wenzhou Institute of Biomaterials and Engineering, Wenzhou Medical Uni

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